238000000227 grinding Methods 0.000 claims abstract description 20.241000271566 Aves Species 0.000 claims abstract description 36.NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 65.244000144992 flock Species 0.000 claims abstract description 66.210000003746 Feathers Anatomy 0.000 claims abstract description 66.238000009472 formulation Methods 0.000 claims abstract description 68.150000001875 compounds Chemical class 0.000 claims abstract description 77.239000000463 material Substances 0.000 claims abstract description 152.239000000203 mixture Substances 0.000 claims abstract description 179.LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 211.239000011159 matrix material Substances 0.000 claims abstract description 246.230000000144 pharmacologic effect Effects 0.000 claims abstract description 251.239000003795 chemical substances by application Substances 0.000 title description 50.239000002552 dosage form Substances 0.000 title claims abstract description 484.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from EP12002708.1 external-priority Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH Publication of CN104394851A publication Critical patent/CN104394851A/en Application granted granted Critical Publication of CN104394851B publication Critical patent/CN104394851B/en Status Active legal-status Critical Current Anticipated expiration legal-status Critical Links Original Assignee Gruenenthal GmbH Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) ( en Inventor K.维宁 L.巴恩沙伊德 S.施维尔 Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Active Application number CN201380020860.5A Other languages Chinese ( zh)
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Google Patents Anti-distort and anti-agent amount are come down in torrents pharmaceutical dosage formĭownload PDF Info Publication number CN104394851B CN104394851B CN201380020860.5A CN201380020860A CN104394851B CN 104394851 B CN104394851 B CN 104394851B CN 201380020860 A CN201380020860 A CN 201380020860A CN 104394851 B CN104394851 B CN 104394851B Authority CN China Prior art keywords weight dosage form pharmaceutical dosage particle pharmacological component Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents CN104394851B - Anti-distort and anti-agent amount are come down in torrents pharmaceutical dosage form CN104394851B - Anti-distort and anti-agent amount are come down in torrents pharmaceutical dosage form
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